In the 21st century, it is clear that manual dissection and records now represent an anachronistic approach to specimen handling. We envision a streamlined system where automated tissue preparation enhances accuracy while removing overhead and bottlenecks, and sterile, smart containers are used in Operating Rooms for tumor removal procedures – capturing vital specimen data, ensuring precise tissue cutting, and with seamless LIS integration. These metrics will chronicle the quantitative records for patients as they move through cancer treatment protocols that are becoming far more personalized, efficient, and accessible.